2010 - 2011 Cleveland Cavaliers Schedule
October 2010
| Date | Opponent | Time |
| Tue, Oct 5 | Charlotte Bobcats (P) | 7:00 pm |
| Thu, Oct 7 | Washington Wizards (P) | 7:00 pm |
| Sun, Oct 10 | at Houston Rockets (P) | 7:00 pm |
| Mon, Oct 11 | at Dallas Mavericks (P) | 8:30 pm |
| Thu, Oct 14 | San Antonio Spurs (P) | 7:30 pm |
| Tue, Oct 19 | Philadelphia 76ers (P) | 7:00 pm |
| Thu, Oct 21 | Milwaukee Bucks (P) | 7:00 pm |
| Wed, Oct 27 | Boston Celtics | 7:00 pm |
| Fri, Oct 29 | at Toronto Raptors | 7:00 pm |
| Sat, Oct 30 | Sacramento Kings | 7:30 pm |
November 2010
| Date | Opponent | Time |
| Tue, Nov 2 | Atlanta Hawks | 7:00 pm |
| Fri, Nov 5 | at Philadelphia 76ers | 7:00 pm |
| Sat, Nov 6 | at Washington Wizards | 7:00 pm |
| Tue, Nov 9 | at New Jersey Nets | 7:00 pm |
| Wed, Nov 10 | New Jersey Nets | 7:30 pm |
| Sat, Nov 13 | Indiana Pacers | 7:30 pm |
| Tue, Nov 16 | Philadelphia 76ers | 7:00 pm |
| Fri, Nov 19 | at New Orleans Hornets | 8:00 pm |
| Sat, Nov 20 | at San Antonio Spurs | 8:30 pm |
| Tue, Nov 23 | at Indiana Pacers | 7:00 pm |
| Wed, Nov 24 | Milwaukee Bucks | 7:00 pm |
| Fri, Nov 26 | at Orlando Magic | 7:00 pm |
| Sat, Nov 27 | Memphis Grizzlies | 7:30 pm |
| Tue, Nov 30 | Boston Celtics | 7:00 pm |
December 2010
| Date | Opponent | Time |
| Thu, Dec 2 | Miami Heat | 8:00 pm |
| Sat, Dec 4 | at Minnesota Timberwolves | 8:00 pm |
| Sun, Dec 5 | at Detroit Pistons | 6:00 pm |
| Tue, Dec 7 | at Philadelphia 76ers | 7:00 pm |
| Wed, Dec 8 | Chicago Bulls | 7:00 pm |
| Sat, Dec 11 | at Houston Rockets | 8:30 pm |
| Sun, Dec 12 | at Oklahoma City Thunder | 7:00 pm |
| Wed, Dec 15 | at Miami Heat | 7:30 pm |
| Fri, Dec 17 | at Indiana Pacers | 7:00 pm |
| Sat, Dec 18 | New York Knicks | 7:30 pm |
| Mon, Dec 20 | Utah Jazz | 7:00 pm |
| Wed, Dec 22 | at Atlanta Hawks | 7:00 pm |
| Sun, Dec 26 | Minnesota Timberwolves | 6:00 pm |
| Tue, Dec 28 | Orlando Magic | 7:00 pm |
| Wed, Dec 29 | at Charlotte Bobcats | 7:00 pm |
January 2011
| Date | Opponent | Time |
| Sat, Jan 1 | at Chicago Bulls | 7:00 pm |
| Sun, Jan 2 | Dallas Mavericks | 7:00 pm |
| Wed, Jan 5 | Toronto Raptors | 7:00 pm |
| Fri, Jan 7 | at Golden State Warriors | 10:30 pm |
| Sun, Jan 9 | at Phoenix Suns | 8:00 pm |
| Tue, Jan 11 | at Los Angeles Lakers | 10:03 pm |
| Fri, Jan 14 | at Utah Jazz | 9:00 pm |
| Sat, Jan 15 | at Denver Nuggets | 9:00 pm |
| Wed, Jan 19 | Phoenix Suns | 7:00 pm |
| Fri, Jan 21 | Milwaukee Bucks | 7:30 pm |
| Sat, Jan 22 | at Chicago Bulls | 8:00 pm |
| Mon, Jan 24 | at New Jersey Nets | 7:00 pm |
| Tue, Jan 25 | at Boston Celtics | 7:30 pm |
| Fri, Jan 28 | Denver Nuggets | 7:30 pm |
| Sun, Jan 30 | at Orlando Magic | 6:00 pm |
| Mon, Jan 31 | at Miami Heat | 7:30 pm |
February 2011
| Date | Opponent | Time |
| Wed, Feb 2 | Indiana Pacers | 7:00 pm |
| Fri, Feb 4 | at Memphis Grizzlies | 8:00 pm |
| Sat, Feb 5 | Portland Trail Blazers | 7:30 pm |
| Mon, Feb 7 | at Dallas Mavericks | 8:30 pm |
| Wed, Feb 9 | Detroit Pistons | 7:00 pm |
| Fri, Feb 11 | Los Angeles Clippers | 7:30 pm |
| Sun, Feb 13 | Washington Wizards | 6:00 pm |
| Wed, Feb 16 | Los Angeles Lakers | 7:30 pm |
| Wed, Feb 23 | Houston Rockets | 7:00 pm |
| Fri, Feb 25 | New York Knicks | 7:30 pm |
| Sun, Feb 27 | Philadelphia 76ers | 5:00 pm |
March 2011
| Date | Opponent | Time |
| Wed, Mar 2 | San Antonio Spurs | 7:00 pm |
| Fri, Mar 4 | at New York Knicks | 7:30 pm |
| Sun, Mar 6 | New Orleans Hornets | 6:30 pm |
| Tue, Mar 8 | Golden State Warriors | 7:00 pm |
| Wed, Mar 9 | at Milwaukee Bucks | 8:00 pm |
| Sun, Mar 13 | Oklahoma City Thunder | 1:00 pm |
| Wed, Mar 16 | at Sacramento Kings | 10:00 pm |
| Thu, Mar 17 | at Portland Trail Blazers | 10:00 pm |
| Sat, Mar 19 | at Los Angeles Clippers | 3:30 pm |
| Mon, Mar 21 | Orlando Magic | 7:00 pm |
| Wed, Mar 23 | New Jersey Nets | 7:00 pm |
| Fri, Mar 25 | Detroit Pistons | 7:30 pm |
| Sun, Mar 27 | Atlanta Hawks | 6:00 pm |
| Tue, Mar 29 | Miami Heat | 7:00 pm |
| Wed, Mar 30 | at Charlotte Bobcats | 7:00 pm |
April 2011
| Date | Opponent | Time |
| Fri, Apr 1 | at Washington Wizards | 7:00 pm |
| Sun, Apr 3 | at New York Knicks | 6:00 pm |
| Tue, Apr 5 | Charlotte Bobcats | 7:00 pm |
| Wed, Apr 6 | at Toronto Raptors | 7:00 pm |
| Fri, Apr 8 | Chicago Bulls | 7:30 pm |
| Sat, Apr 9 | at Milwaukee Bucks | 8:30 pm |
| Mon, Apr 11 | at Detroit Pistons | 7:30 pm |
| Wed, Apr 13 | Washington Wizards | 8:00 pm |
